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❀Direction for use
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1. The recommended adult dose:
- Taken by mouth: 13 to 16 mg per kilogram of body weight per day, given in 2 divided doses, should be taken with food or milk in the morning and the evenning . The daily dose may be divided unevenly and taking more doses at bedtime to neutralize overnight increases in bile cholesterol levels.
The starting dose of ursodiol is 250 mg, given in 2 doses in 2 week of treatment, then increased by 250mg a day per week up to reach the recommended or the maximum tolerable dose.
If diarrhea occur in the dose increase process or in the end of treatment, adjust the dose until diarrhea cleared , then back to the old dose.
The fat patient (overweight) can need a dose of 20 mg per kilogram of body weight per day.
2.The regularly treatment dose of using this medication have not been established for children.
3. Notice:
Depending on the size and composition of cholesterol gallstones, the treatment could be taken from 3 months to 2 years. Every 3 to 9 months, take an X-ray of the gallbladder or an ultrasound to monitor the response to the medicine.The treatment can be taken up to 2 years, depending on the size of the gallstone; should be continued about 3 months after the X-ray without gallstone.
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